RecruitingNot ApplicableNCT05763732

Effects of RAS on Gait in PD Patients With DBS

Effects of Rhythmic Auditory Stimulation (RAS) on Gait in Parkinson Disease (PD) Patients With DBS

Sponsor

Johns Hopkins University

Enrollment

10 participants

Start Date

Aug 1, 2023

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease

Summary

Participants will be asked to walk along with the metronome beats (RAS) during the participants' stimulation state (ON or OFF) for four minutes for each state. The researcher will collect the gait parameters (cadence, velocity, and stride length) of patients before, during, and after RAS in both DBS ON and OFF states. Using MDS-UPDRS, participants' gait patterns will be collected before and after RAS while both DBS is ON and OFF. Electrophysiological activity (local field potentials, LFPs) will be collected across all stages (pre, during, and post-RAS) of evaluation.

Eligibility

Min Age: 18 YearsMax Age: 89 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether rhythmic auditory stimulation (RAS) — using rhythmic sounds or music to cue movement — improves how people with Parkinson's disease walk, in patients who have a deep brain stimulation (DBS) implant. DBS delivers electrical signals to specific brain areas to reduce symptoms. **You may be eligible if...** - You have been diagnosed with Parkinson's disease - You have had a specific type of deep brain stimulation device (Percept PC by Medtronic) implanted in your subthalamic nucleus **You may NOT be eligible if...** - You are unable or unwilling to follow study instructions and procedures Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALRhythmic Auditory Stimulation (RAS)

Rhythmic auditory stimulus (RAS) is a Neurologic Music Therapy (NMT) technique that utilizes an auditory rhythmic cue to entrain gait to a specific rhythm. RAS, as an anticipatory time cue, can be used as both an immediate entrainment stimulus, providing rhythmic cues during movement, and as a facilitating stimulus for planning and executing a movement to achieve more functional gait patterns. Cadence, gait velocity, and stride length are the commonly used parameters to monitor changes in a patient's gait.