RecoverPC: Relugolix vs GnRH Agonist in Quality of Life

This study compares two hormone-suppression treatments for prostate cancer — an older monthly injection (leuprolide) versus a newer daily pill (relugolix) — to see which is better for quality of life, including heart health and sexual function. **You may be eligible if...** - You have been diagnosed with prostate cancer (confirmed by biopsy) - You are a candidate for 6 months of hormone therapy - You have not had prior hormone therapy (GnRH agonist or antagonist) - Your testosterone level is above 200 ng/mL before starting treatment **You may NOT be eligible if...** - You have already received GnRH agonist or antagonist treatment - You need additional systemic cancer treatments beyond hormone therapy and first-generation anti-androgens Talk to your doctor to see if this trial is right for you.