RecruitingNot ApplicableNCT05773144
Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer
Sponsor
AdventHealth Translational Research Institute
Enrollment
219 participants
Start Date
Jun 1, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.
Eligibility
Min Age: 18 Years
Inclusion Criteria12
- Age ≥18 years
- Histologically confirmed stage II or III colon cancer
- Completed surgical resection with curative intent
- Plan to initiate chemotherapy
- Engage in \<60 minutes per week of moderate- to vigorous-intensity structured aerobic exercise
- No planned major surgery during the study period
- Readiness to exercise, as determined by a modified version of the Physical Activity Readiness Questionnaire
- Can walk 400 meters
- Can read and speak English
- Ability to provide written informed consent
- Provide written approval by qualified healthcare professional
- Willing to be randomized
Exclusion Criteria6
- Evidence of metastatic colon cancer
- Concurrently actively treated other (non-colon) cancer
- Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks
- Currently participating in another study with competing outcomes
- Any other condition that, in the opinion of the investigator, would preclude participation or successful compliance with the protocol
- Any other situation that, in the opinion of the investigator, would negatively impact subject safety or successful compliance with the protocol
Interventions
BEHAVIORALAerobic exercise
Moderate- to vigorous-intensity aerobic exercise
BEHAVIORALProgressive stretching
Static stretching of eight major muscle groups
Locations(3)
View Full Details on ClinicalTrials.gov
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NCT05773144
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