Ambroxol to Slow Progression in Parkinson Disease

This study is testing whether ambroxol — a drug commonly used for coughs — can slow the progression of Parkinson's disease. Ambroxol activates an enzyme that may clear out a protein thought to drive Parkinson's, and researchers want to see whether it can meaningfully affect disease progression, especially in people with a genetic variant (GBA1 gene) associated with increased Parkinson's risk. **You may be eligible if:** - You have been diagnosed with Parkinson's disease within the last 7 years - You are between 35 and 75 years old - Your Parkinson's symptoms are mild to moderate (Hoehn and Yahr stage 1–2.5) - You have confirmed GBA1 gene status (positive or negative — both are eligible) - You have been on a stable Parkinson's medication regimen for at least 3 months **You may NOT be eligible if:** - Your Parkinson's was diagnosed more than 7 years ago - You have more advanced disease (Hoehn and Yahr stage above 2.5) - You are under 35 or over 75 years old - Your GBA1 status has not been confirmed Talk to your doctor to see if this trial is right for you.