RecruitingNot ApplicableNCT05778708

Tai-Chi and Aerobic Exercise to Improve Emotional Symptom Cluster in Late-stage Lung Cancer Patients


Sponsor

The University of Hong Kong

Enrollment

318 participants

Start Date

Mar 13, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized controlled trial is to investigate the effects of Tai-Chi and aerobic exercise on the emotional symptom cluster, and the underlying mechanism of that cluster, in late-stage lung cancer patients. Participants will be randomized into one of three groups: 1) Tai-Chi group, 2) aerobic exercise group, or 3) self-management control group. Both the Tai-Chi and aerobic exercise groups will attend twice-weekly group classes for 16 weeks (32 total contact hours). The self-management control group will receive written information regarding the recommended level of physical activity.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • diagnosed with stage IIIB or IV non-small cell lung cancer confirmed by pathology, with no other cancer diagnosis within the previous year;
  • a current Eastern Cooperative Oncology Group Performance Status of 0-2;
  • experience of sleep disturbance, anxiety, depression, and fatigue in the past week (rating of 1 or more on a 0-10 numeric rating scale \[NRS\] for each symptom);
  • able to communicate in Cantonese, Mandarin, or English;
  • conscious and alert

Exclusion Criteria2

  • suffering from a condition that hinders exercise performance (e.g., active neurological disorder, recent heart attack);
  • currently participating in any other exercise or mind-body classes; or 3) performing regular exercises, defined as at least 150 minutes of moderate-intensity exercise weekly

Interventions

BEHAVIORALTai-Chi intervention

The standardized 16-form Yang-style Tai-Chi exercise set will be adopted. Group classes will take place in a community center twice a week for 16 weeks, with each class lasting approximately 60 minutes. Classes will be taught by an experienced Tai-Chi master. Patients will be instructed to practice the Tai-Chi exercises at home at least 3 times a week (30 min each time for a total of 90 min). Patients will be provided with a daily exercise log to record their exercise type, frequency, and intensity.

BEHAVIORALAerobic exercise intervention

The aerobic exercise class will be designed to cover both aerobic and resistance exercises. Group classes will take place in an exercise center twice a week for 16 weeks, with each class lasting approximately 60 minutes. Each class will be led by a certified exercise specialist. Patients will be provided with a daily exercise log to record their exercise type, frequency, and intensity.


Locations(1)

Queen Mary Hospital

Hong Kong, Hong Kong

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NCT05778708


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