RecruitingNot ApplicableNCT05778708

Tai-Chi and Aerobic Exercise to Improve Emotional Symptom Cluster in Late-stage Lung Cancer Patients


Sponsor

The University of Hong Kong

Enrollment

318 participants

Start Date

Mar 13, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized controlled trial is to investigate the effects of Tai-Chi and aerobic exercise on the emotional symptom cluster, and the underlying mechanism of that cluster, in late-stage lung cancer patients. Participants will be randomized into one of three groups: 1) Tai-Chi group, 2) aerobic exercise group, or 3) self-management control group. Both the Tai-Chi and aerobic exercise groups will attend twice-weekly group classes for 16 weeks (32 total contact hours). The self-management control group will receive written information regarding the recommended level of physical activity.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether Tai Chi and aerobic exercise can reduce emotional symptoms in people with late-stage lung cancer. Many cancer patients experience sleep problems, anxiety, depression, and fatigue together — a cluster of symptoms that significantly affects quality of life. Researchers want to see if structured exercise can help. **You may be eligible if:** - You have been diagnosed with stage IIIB or IV non-small cell lung cancer confirmed by biopsy - You have no other cancer diagnosis in the past year - You are experiencing sleep disturbances, anxiety, depression, and fatigue (even mild, rated 1 or above on a 0–10 scale) - You can communicate in Cantonese, Mandarin, or English - Your general health allows for light to moderate exercise (ECOG performance status 0–2) **You may NOT be eligible if:** - You have a condition that prevents you from exercising (e.g., active neurological disorder) - You cannot follow instructions for safe exercise participation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALTai-Chi intervention

The standardized 16-form Yang-style Tai-Chi exercise set will be adopted. Group classes will take place in a community center twice a week for 16 weeks, with each class lasting approximately 60 minutes. Classes will be taught by an experienced Tai-Chi master. Patients will be instructed to practice the Tai-Chi exercises at home at least 3 times a week (30 min each time for a total of 90 min). Patients will be provided with a daily exercise log to record their exercise type, frequency, and intensity.

BEHAVIORALAerobic exercise intervention

The aerobic exercise class will be designed to cover both aerobic and resistance exercises. Group classes will take place in an exercise center twice a week for 16 weeks, with each class lasting approximately 60 minutes. Each class will be led by a certified exercise specialist. Patients will be provided with a daily exercise log to record their exercise type, frequency, and intensity.


Locations(1)

Queen Mary Hospital

Hong Kong, Hong Kong

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NCT05778708


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