Food Genetics Behavior Study
Role of Energy Balance Behaviors in Modifying Biobehavioral Risk Factors for Childhood Obesity
University of Pennsylvania
242 participants
Jul 26, 2023
INTERVENTIONAL
Conditions
Summary
A genetic risk for obesity does not always translate to the development of obesity among children, which points to the presence of risk-modifying factors that likely relate to energy balance behaviors as key behavioral drivers. Using an integrated approach to comprehensively examine the interplay between genotype and phenotype, this study will systematically assess the extent to which energy balance behaviors, alone or in combination, in conjunction with family-level influences can modify behavioral and genetic predispositions to childhood obesity in a high-risk sample of predominantly minority children from low-resource backgrounds. Identifying protective factors that may mitigate the impact of obesity risk on weight and adiposity outcomes is critical for moving the prevention of childhood obesity into a new direction.
Eligibility
Inclusion Criteria5
- Healthy children
- Children ages 5-7 years
- Children with BMI equal to or greater 5th percentile
- Mother must be children's biological mother and primary caregiver
- Mother must be able to read and understand English
Exclusion Criteria4
- Children with serious medical conditions or medication use known to affect food intake, body weight, physical activity, or sleep
- Children with developmental and/or psychiatric conditions that may impact study compliance
- Children with food allergies related to study foods or lactose intolerance
- Children with low preference for study foods
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Interventions
Participants' eating rate and eating in the absence of hunger will be assessed during a videotaped experimental meal. The relative reinforcing value of food will be assessed using a computerized behavioral choice task.
Locations(1)
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NCT05783765