RecruitingNot ApplicableNCT05794152

Wenzhou Gestational Diabetes Cohort


Sponsor

Westlake University

Enrollment

300 participants

Start Date

Mar 21, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The Wenzhou Gestational Diabetes Cohort (WGDC) is a prospective cohort study among women with gestational diabetes mellitus (GDM) during pregnancy and their offspring living in Wenzhou, China. The primary aim of this cohort is to characterize the continuous blood glucose response to dietary intake and physical activity among pregnant women with GDM over 2 weeks, and to facilitate the development of personalized nutritional/lifestyle recommendation among these patients. Another aim of the WGDC is to investigate the association of dietary and physical activity together with continuous glucose change during pregnancy on the adverse birth outcomes including preterm birth, macrosomia and large-for-gestational-age birth. The secondary aim is to investigate the prospective associations of diet, physical activity and continuous glucose change over 2 weeks among the patients with long-term metabolic health of the women and their offspring.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria4

  • Women aged 18 years or older
  • Women with GDM mainly at 24-28 weeks of gestation
  • Women intended to deliver at Wenzhou People's Hospital
  • Women intended to remain in Wenzhou with their child for ≥4 years

Exclusion Criteria1

  • Women with cancer and other serious medical disorders

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Interventions

OTHERStandardized breakfast

Participants will be provided with a standardized breakfast on a morning of the days they wear a continuous glucose monitoring (CGM) device.

OTHERStandardized snack

Participants will be provided with a standardized snack 2 hour after they have the standardized breakfast.

OTHERStandardized lunch

Participants will be provided with a standardized lunch 2 h after they have the standardized snack.


Locations(1)

Wenzhou People's Hospital

Wenzhou, Zhejiang, China

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NCT05794152


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