RecruitingPhase 4NCT05806580

Secondary Infusion of Relma-cel Injection for Relapsed or Refractory B-cell Lymphoma

A Single-arm Prospective Study of Secondary Infusion of Relmacabtagene Autoleucel Injection for Relapsed or Refractory B-cell Lymphoma


Sponsor

Ruijin Hospital

Enrollment

8 participants

Start Date

May 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

To observe the efficacy and safety of a second infusion of relma-cel injection in patients with relapsed or refractory B-cell lymphoma.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at giving a second infusion of a CAR-T cell therapy called Relma-cel to patients with B-cell lymphoma whose cancer progressed, stabilized without full remission, or partially responded after the first round of this treatment. **You may be eligible if...** - You are an adult with relapsed or treatment-resistant B-cell lymphoma - You have already completed an initial treatment course with Relma-cel (CAR-T therapy) - Your doctor has assessed your disease at least once since the first treatment - Your doctor recommends a second round based on your clinical situation - Enough Relma-cel is available for a second dose **You may NOT be eligible if...** - You have not previously received Relma-cel - You achieved a complete response (full remission) after the first infusion with no signs of relapse - Your health is too poor to tolerate another round of CAR-T therapy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGRelma-cel

Patients who have undergone at least one disease assessment after initial Relma-cel treatment and have not achieved complete remission may receive a second treatment based on clinical practice. The specific dosage will be determined by the investigator according to the patient's condition and available dose reserves.


Locations(1)

NO.197, Ruijin Er Road

Shanghai, Shanghai Municipality, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05806580