RecruitingNCT05817864

Diagnostic Accuracy of Capnography in Nasogastric Tube Placement

Diagnostic Accuracy of Using Capnography in Verification of Nasogastric Tube Placement in Hospital Settings


Sponsor

Chinese University of Hong Kong

Enrollment

390 participants

Start Date

Jul 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

A prospective observational diagnostic study will be conducted to assess the sensitivity and specificity of using capnography in detecting the correct placement of nasogastric tubes using the reference standards of radiography and measurement of aspirates for pH value.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • years old or above;
  • Admitted to the general medical and geriatric wards, ICUs, or subacute/rehabilitation/infirmary wards in subacute/convalescent/extended care hospitals or visiting AEDs in acute hospitals;
  • Requiring the insertion of an nasogastric tube into the stomach for assessment, nutritional support and medication administration during the study period.

Exclusion Criteria1

  • Participants receiving life-saving intervention at the time of recruitment.

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Interventions

DIAGNOSTIC_TESTCapnography

Index test: Capnography, which monitors ETCO2, the percentage concentration, or partial pressure of CO2 at the end of exhalation, will serve as the index test. It will be performed by connecting the end of the nasogastric tube with the sensor of the bedside sidestream capnography device. Placement within the airway is defined as detecting a capnogram waveform or an ETCO2 level \> 10 mmHg. Reference standard: This study will use radiography (chest/abdominal X-ray) as the reference standard for determining the correct placement of nasogastric tubes. Radiology will be performed as soon as possible and interpreted by a physician. A repeat radiography will be performed if necessary. We will also use pH-Fix-4.5-10 to determine the pH value, and its accuracy is +/- 0.2 pH with minimum increments of 0.5. A pH of 5.5 or below indicates gastric placement.


Locations(1)

The Chinese University of Hong Kong

Hong Kong, Hong Kong SAR, China

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NCT05817864


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