RecruitingNot ApplicableNCT05818605

Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy

The EXerCise traIning To rEcovery in HCM Trial

Sponsor

University of California, San Francisco

Enrollment

70 participants

Start Date

Feb 17, 2023

Study Type

INTERVENTIONAL

Conditions

Hypertrophic Cardiomyopathy

Summary

The EXCITE-HCM study is a randomized, controlled, blinded clinical trial designed to evaluate the effect of moderate intensity exercise training versus usual physicial activity on the improvement of HCM-related symptoms and cardiac function. About 70 participants will be recruited and randomized on a 1:1 ratio to either moderate intensity training or usual physicial activity interventions. Patients will be followed during a period of 24 weeks and assesesments as physical examination, questionnaires, 12 lead ecg's, biomarker levels, echocardiogram, Cardiac Magnetic resonance, PET and CPET will be performed to evaluate their response to the intervention.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Moderate Intensity Exercise Program for people with hypertrophic cardiomyopathy. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALModerate Intensity Exercise Program

Subjects randomized to the EXER arm will undergo 24 weeks of Moderate Intensity Exercise Training (MIET). Patients will be signed up for 60-minute exercise sessions, 3 times a week