RecruitingNot ApplicableNCT05822037

CT0594CP CAR-T Cells in Patients With Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia

Exploratory Study to Assess the Safety and Efficacy of CT0594CP CAR-T Cells in Patients With Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia


Sponsor

The First Affiliated Hospital of Soochow University

Enrollment

6 participants

Start Date

Apr 12, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This is an open-label, single arm study to evaluate the safety and tolerability of treatment with CT0594CP CAR-T Cells in patients with relapsed and/or refractory multiple myeloma or Plasma Cell Leukemia


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study tests CT0594CP, a type of CAR-T cell therapy — where a patient's own immune cells are genetically engineered to attack cancer cells — for people with multiple myeloma or plasma cell leukemia that has come back or stopped responding to previous treatments. CAR-T therapy is a cutting-edge approach that reprograms the immune system to fight blood cancers. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with multiple myeloma or plasma cell leukemia - Your cancer has relapsed or become resistant after prior treatment - Your cancer is measurable (detectable levels of abnormal protein in blood or urine) - Your overall health is acceptable (ECOG 0–2) **You may NOT be eligible if...** - You have active serious infections or uncontrolled illnesses - You have had prior CAR-T cell therapy or allogeneic stem cell transplant - Your major organs (heart, liver, kidneys, lungs) are not functioning adequately - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALCT0594CP

Cell injection


Locations(1)

First Affiliated Hospital, Soochow University

Suzhou, Jiangsu, China

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NCT05822037


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