RecruitingNot ApplicableNCT05829889

Fractional Flow Reserve Versus Angiography for Treatment-Decision and Evaluation of Significant Left MAIN Coronary Artery Disease

A Comparison of Fractional Flow Reserve- Versus Angiography-Guided Percutaneous Coronary Intervention in Patients With Left Main Coronary Artery Disease

Sponsor

Seung-Jung Park

Enrollment

960 participants

Start Date

Apr 25, 2024

Study Type

INTERVENTIONAL

Conditions

Coronary Artery Disease Coronary Artery Disease (Left Main)

Summary

The primary purpose of the study was to determine whether the 2-year probability of major adverse cardiac events (primary composite outcome) differed significantly between patients who underwent angiography-guided Percutaneous Coronary Intervention(PCI) and those who underwent Fractional Flow Reserve(FFR)-guided PCI in patients with Left Main Coronary Artery disease(LMCA).

Eligibility

Min Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Angiography-Guided PCI and a procedure called FFR-Guided PCI for people with coronary artery disease and coronary artery disease (left main). The study is currently recruiting participants at 49 locations. People eligible for this study include aged 20 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREFFR-Guided PCI

Fractional Flow Reserve-Guided PCI

PROCEDUREAngiography-Guided PCI

Angiography-Guided PCI

Locations(49)

Princess Margret Hospital( HongKong)

Hong Kong, Hong Kong

Queen Mary Hospital

Hong Kong, Hong Kong

Manipal Hospital

Bangalore, India

Japanese Red Cross Musashino Hospital

Tokyo, Japan

NTT East Japan Kanto Hospital

Tokyo, Japan

Tsuchiura Kyodo General Hospital

Tsuchiura, Japan

Asan Medical Center

Seoul, Songpa-gu, South Korea

Korea University Ansan Hospital

Ansan, South Korea

Hallym University Sacred Heart Hospital

Anyang, South Korea

Bucheon Sejong Hospital

Bucheon-si, South Korea

Dong-A University Hospital

Busan, South Korea

Pusan National University Hospital

Busan, South Korea

Pusan National University Yangsan Hospital

Busan, South Korea

Changwon Gyeongsang National University Hospital

Changwon, South Korea

Kangwon National University Hospital

Chuncheon, South Korea

Daegu Catholic University Medical Center

Daegu, South Korea

Keimyung University Dongsan Medical Center

Daegu, South Korea

Yeungnam University Hospital

Daegu, South Korea

Chungnam National University Hospital

Daejeon, South Korea

Daejeon St. Mary's Hospital, Catholic University of Korea

Daejeon, South Korea

Gangneung Asan Hospital

Gangneung, South Korea

Chonnam National University Hospital

Gwangju, South Korea

Chung-Ang University Gwangmyeong Hospital

Gwangmyeong, South Korea

Hallym University Dongtan Sacred Heart Hospital

Hwaseong-si, South Korea

CHA Ilsan Medical Center

Ilsan, South Korea

Ilsan Myongji Hospital

Ilsan, South Korea

Inje University Ilsan Paik Hospital

Ilsan, South Korea

National Health Insurance Service Ilsan Hospital

Ilsan, South Korea

Gachon University Gil Medical Center

Incheon, South Korea

Inha University Hospital

Incheon, South Korea

Jeju National University Hospital

Jeju City, South Korea

Chungnam National University Sejong Hospital

Seongam, South Korea

Seoul National University Bundang Hospital

Seongnam, South Korea

Chung-Ang University Hospital

Seoul, South Korea

Eunpyeong St. Mary's Hospital, Catholic University of Korea

Seoul, South Korea

Hanyang University Hospital

Seoul, South Korea

Kangbuk Samsung Hospital

Seoul, South Korea

Korea University Anam Hospital

Seoul, South Korea

Korea University Guro Hospital

Seoul, South Korea

Kyung Hee University Hospital

Seoul, South Korea

Seoul Metropolitan Boramae Hospital

Seoul, South Korea

Seoul National University Hospital

Seoul, South Korea

Soonchunhyang University Seoul Hospital

Seoul, South Korea

Yeouido St. Mary's Hospital, Catholic University of Korea

Seoul, South Korea

Ajou University Hospital

Suwon, South Korea

St. Vincent's Hospital, Catholic University of Korea

Suwon, South Korea

Ulsan University Hospital

Ulsan, South Korea

Yongin Severance Hospital

Yongin, South Korea

Cheng Hsin General Hospital

Taipei, Taiwan

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NCT05829889

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