RecruitingNot ApplicableNCT05831709

The Influence of Hormone Replacement Therapy and Supervised Exercise Training on Body Composition, Cardiovascular Risk and Insulin Sensitivity in Postmenopausal Women

De Invloed Van Hormoonsubstitutietherapie en Gesuperviseerde Training op Lichaamssamenstelling, Cardiovasculair Risico en Insulinegevoeligheid Bij Postmenopauzale Vrouwen


Sponsor

University Hospital, Ghent

Enrollment

390 participants

Start Date

May 12, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This trial investigates whether supervised training in combination with hormonal substitution therapy has an impact on body composition, cardiovascular risk, risk for dementia, osteoporosis and insulin sensitivity in postmenopausal women.


Eligibility

Sex: FEMALEMin Age: 45 YearsMax Age: 65 Years

Inclusion Criteria5

  • Postmenopausal women (diagnosed by physician) with complaints due to menopause
  • Indication for hormonal substitution therapy (except for the control group)
  • Good general health
  • BMI: 20-30 kg/m2
  • Only the use of cholesterol-, blood pressure- or/and thyroid-regulating medication is permitted

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Interventions

OTHERExercise program

The intervention consists of a supervised exercise program

DRUGHormonal substitution therapy per SOC

Subjects take hormonal substitution therapy per standard of care


Locations(1)

Ghent University Hospital - Women's Clinic

Ghent, Belgium

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NCT05831709


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