RecruitingNCT05835349

Observational Study of Venus P-Valve

A Real-World Evidence Observational Study of VenusP-ValveTM System in the Treatment of Patients with Native RVOT Dysfunction


Sponsor

Venus MedTech (HangZhou) Inc.

Enrollment

200 participants

Start Date

Aug 26, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Real-world evidence, retrospective and prospective, non-randomized, multicenter observational study of VenusP-ValveTM System in treating moderate or greater pulmonary regurgitation with/without pulmonary stenosis in patients with native right ventricular outflow tract (RVOT).


Eligibility

Min Age: 12 YearsMax Age: 70 Years

Inclusion Criteria2

  • Patients with native RVOT (including transvalvular patch repair) are present with moderate or greater pulmonary regurgitation with/without stenosis and are clinically indicated for pulmonary valve intervention.
  • The patient (or the patient's legally authorized representative) is willing to consent to participate in the study and will commit to completing all follow-up requirements.

Exclusion Criteria1

  • \. Patients with any condition contraindicated by the IFU or inability to comply with the Venus P-ValveTM System Instructions for Use or the study protocol.

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Interventions

DEVICEtranscatheter pulmonary valve implantation (TPVI)

A stent-mounted valve is introduced over a guidewire and positioned in the RVOT, followed by balloon inflation to deploy the valve.


Locations(10)

CHU Bordeaux

Pessac, New Aquitaine, France

Chu Nantes

Nantes, Pays de la Loire Region, France

Marie Lannelongue

Le Plessis-Robinson, Île-de-France Region, France

Hopital Necker-Enfants malades

Paris, Île-de-France Region, France

Heart CenterMunich

Munich, Bavaria, Germany

Clinic of Congenital Heart Disease

Berlin, State of Berlin, Germany

OPBG Rome

Rome, Lazio, Italy

S. Donato Milan

Milan, Lombardy, Italy

Leeds General Infirmary

Leeds, England, United Kingdom

Evelina Children's Hospital

London, England, United Kingdom

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NCT05835349