Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst?
Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst? A Prospective Study
ART Fertility Clinics LLC
300 participants
May 23, 2023
OBSERVATIONAL
Conditions
Summary
To investigate, whether on the day of egg retrieval, after ovarian stimulation for ICSI (intracytoplasmic sperm injection), there is a correlation between the intrafollicular AMH (Anti-Müllerian hormone) levels and the ploidy status of the blastocyst.
Eligibility
Inclusion Criteria4
- At least one follicle from each ovary at day of trigger
- Age from 18 to 40 years old
- Normal menstrual cycle of 25-35 days
- Poor, normal and high response will be included
Exclusion Criteria5
- Very hematic follicular fluid
- If the COC is not found in the follicular fluid
- Azoospermia
- Known chromosomal abnormalities
- Severe OAT (Oligoasthenoteratozoospermia)
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Interventions
Aspiration of follicles. search for the oocyte(s) All oocytes are grouped in one dish.
All oocytes are denuded together. Maturational stages are recorded.
One oocyte injected at a time.
One embryo per culture drop. Individual follow-up of the embryo development.
One embryo per culture drop.
One embryo per vitrification straw.
Measure the size of the follicle and aspirate only one follicle and flush. The needle before moving to the second ovary. Oocyte included in the study will be cultured separately (each ovary separately too).
Oocyte included in the study will be denuded separately. Maturational stages are recorded per follicle.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05837325