RecruitingNot ApplicableNCT05837429

Low Volume High Intensity Interval Training in Operated Lung Cancer Patients

Comparison of the Effects of Continuous Aerobic Exercise Training and Low Volume High Intensity Interval Training on Cardiopulmonary Exercise Capacity, Autonomic Function and Oxidative Stress in Operated Lung Cancer Patients

Sponsor

Hacettepe University

Enrollment

40 participants

Start Date

Apr 6, 2023

Study Type

INTERVENTIONAL

Conditions

Lung Cancer Non-small Cell Lung Cancer

Summary

Patients included in the study will be randomly divided into 2 groups using appropriate randomization programs. All patients will be given exercise training individually for 24 sessions using a bicycle ergometer under the supervision of a physiotherapist.Patients in the first group will be given exercise training on a bicycle ergometer for 5 minutes warm-up phase at 40% of maximal oxygen consumption (VO2max), 20 minutes exercise phase at 60% of VO2max and 5 minutes cool down phase at 40% of VO2max for a total of 30 minutes. Patients in the second group will be given a warm-up phase for 3 minutes at 50% VO2max, 1 minute at 80-100% VO2max and 1 minute at 50% VO2max in 10 cycles, and finally a cool-down phase for 3 minutes at 50% VO2max. In total, 25 minutes of low-volume high-intensity intermittent exercise training will be given on a bicycle ergometer.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria6

Diagnosed with Non-Small Cell Lung Cancer
Stage 3A and earlier
Operated and at least 6 months have expired since the surgery
Having completed adjuvant treatments such as chemotherapy and radiotherapy and at least 6 months have expired
Being clinically stable and in remission
Not having new recurrence and active cancer

Exclusion Criteria4

Pneumonectomy surgery
Presence of symptoms, signs and diagnoses indicating the presence of lung and cardiac disease such as advanced COPD
Having any orthopedic or neurological problem that may prevent exercise
Presence of recurrence or active cancer

Interventions

BEHAVIORALLow Volume High Intensity Exercise Training

Patients in the intervention group will be given a warm-up phase for 3 minutes at 50% VO2max, 1 minute at 80-100% VO2max and 1 minute at 50% VO2max in 10 cycles, and finally a cool-down phase for 3 minutes at 50% VO2max.

BEHAVIORALAerobic Exercise Training

Patients in the control group will be given exercise training on a bicycle ergometer for 5 minutes warm-up phase at 40% of maximal oxygen consumption (VO2max), 20 minutes exercise phase at 60% of VO2max and 5 minutes cool down phase at 40% of VO2max for a total of 30 minutes.