Pulmonary Vein Isolation (PVI) Combined With Renal Denervation (RDN) in Atrial Fibrillation (AF) and Hypertension (HTN)

This study combines two heart procedures in one session for people with both atrial fibrillation (an irregular heartbeat) and high blood pressure: pulmonary vein isolation (a procedure that electrically isolates the areas of the heart causing the irregular rhythm) and renal denervation (a catheter-based procedure that reduces overactive nerve signals driving high blood pressure). **You may be eligible if...** - You are 18 to 75 years old - You have diagnosed atrial fibrillation confirmed on ECG - You have high blood pressure (clinic reading of at least 140/90 mmHg or 24-hour average of at least 135/85 mmHg) **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have significant renal artery problems (stenosis, aneurysm, prior stenting) that make renal denervation unsafe - You have had a recent blood clot, stroke, or heart attack - You have severe kidney disease Talk to your doctor to see if this trial is right for you.