RecruitingNot ApplicableNCT05849844

Tympanoseal Clinical Study

Tympanoseal (Tympanic Membrane Device) Clinical Study


Sponsor

Grace Medical, Inc.

Enrollment

45 participants

Start Date

Jan 5, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this investigational study is to assess the ability of Tympanoseal (sodium/calcium alginate), an investigational device, to act as a scaffold during healing of the tympanic membrane. Tympanoseal is intended for use following removal or extrusion of indwelling tympanostomy tubes or traumatic injury of the tympanic membrane.


Eligibility

Min Age: 2 YearsMax Age: 100 Years

Inclusion Criteria3

  • Male or female patients over 2 years of age at enrollment
  • Documentation of a retained tympanostomy tube or perforation less than 5 mm not on the edge of the tympanic membrane.
  • Written informed consent (and assent when applicable) obtained from subject or subject's legal guardian and ability for subject to comply with the requirements of the study

Exclusion Criteria7

  • Active otorrhea or otitis media
  • Otorrhea or otitis media within 4 weeks prior to the operation
  • History of cholesteatoma
  • Perforations on the edge of the tympanic membrane
  • Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the patient or the quality of the data
  • Subject is taking systemic/oral corticosteroids
  • Subject will require the continued use of any type of topical otic medication to the ear(s) with Tympanoseal

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Interventions

DEVICETympanoseal

All subjects will receive the Tympanoseal device that will be placed during a surgical procedure


Locations(2)

Michigan Ear Institute

Farmington Hills, Michigan, United States

Methodist Le Bonheur

Memphis, Tennessee, United States

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NCT05849844


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