RecruitingNCT05850676

Disentangling the Role of Depression in Hypersomnia


Sponsor

University of Pennsylvania

Enrollment

45 participants

Start Date

Aug 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Individuals who have disorders of hypersomnolence (excessive sleepiness) often report symptoms of depression. The goal of this study is to further understand of the relationship between depression and hypersomnia by examining mood-relevant domains of slow wave sleep and reward function.


Eligibility

Min Age: 21 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at the relationship between depression and hypersomnia — a condition where people sleep excessively and struggle to stay awake during the day. Researchers want to understand whether the sleepiness in some patients is caused primarily by depression or by a separate underlying sleep disorder. **You may be eligible if...** - You are between 21 and 55 years old - You meet the clinical criteria for either idiopathic hypersomnia (excessive sleepiness without a known cause) or hypersomnia associated with a psychiatric disorder - You can read and speak English **You may NOT be eligible if...** - You have untreated obstructive sleep apnea (a sleep disorder where breathing repeatedly stops) - You meet criteria for narcolepsy - You are unable or unwilling to provide consent - You have other medical conditions that could explain your excessive sleepiness (like thyroid problems or medication side effects) - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTSleep study

Participants will spend two nights in the Penn Sleep Center


Locations(1)

The University of Pennsylvania

Philadelphia, Pennsylvania, United States

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NCT05850676