RecruitingNot ApplicableNCT05853094

Postoperative Effects of Different Enterostomy Approaches

A Single-centre, Randomized Study to Compare the Outcomes of Protected Transverse Colostomy Versus Ileostomy After Low Anterior Resection of Low Rectal Cancer From the Perspective of Intestinal Microecology


Sponsor

Fudan University

Enrollment

300 participants

Start Date

Jun 23, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Exploring the effect of protective ileostomy compared with transverse colostomy on the occurrence of complications, the occurrence of serious side effects of adjuvant chemotherapy and disease recurrence in patients with low rectal cancer after radical surgery from the perspective of intestinal microecology.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing different surgical approaches for creating a stoma (an opening in the abdomen to redirect the bowel) in people who have surgery for rectal cancer. It aims to find which approach causes fewer complications and leads to better recovery. **You may be eligible if...** - You are between 18 and 80 years old - You have been diagnosed with rectal cancer (adenocarcinoma), confirmed by tissue sample - Your cancer is stage I, II, or III (not spread to distant organs) - You are in reasonably good health **You may NOT be eligible if...** - You have a rare type of rectal cancer (not adenocarcinoma) - You have cancer in multiple locations or distant spread (metastases) - You have serious heart, lung, liver, or kidney disease - Your surgery required emergency intervention (obstruction, bleeding, or perforation) - You have active infections Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREIleostomy

Protective loop ileostomy after low anterior resection

PROCEDURETransverse colostomy

Protective loop transverse colostomy after low anterior resection


Locations(1)

Fudan University Shanghai Cancer Center

Shanghai, China

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NCT05853094


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