RecruitingNCT05854303

Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction

Prospective Evaluation of the Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction (OIED)


Sponsor

Mayo Clinic

Enrollment

26 participants

Start Date

Sep 18, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to evaluate the effect of opioid cessation on opioid-induced esophageal dysfunction (OIED).


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • \- Patients enrolled in the Pain Rehabilitation Center for opioid cessation, with or without esophageal symptoms.

Exclusion Criteria9

  • Inability to provide informed consent.
  • Patients with previous gastroesophageal surgery or pneumatic dilation.
  • Esophageal botulinum toxin injection within the prior 12 months.
  • Esophageal stricture
  • Achalasia types I and II
  • Allergy to Lidocaine or other local anesthetics
  • Subjects on anticoagulation
  • Bilateral nasal obstruction
  • Pregnancy or breast feeding

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Interventions

BEHAVIORALOpioid cessation

opioid cessation will occur during pain rehabilitative program over approximately 3 weeks

OTHERNo opioid cessation

Subjects will not stop taking opioids


Locations(1)

Mayo Clinic Minnesota

Rochester, Minnesota, United States

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NCT05854303