RecruitingNot ApplicableNCT05855031

The Liver Care Trial

The Liver Care Trial: Screening for Liver Disease in Individuals Attending Treatment for Alcohol Use Disorder - a Randomized Controlled Study


Sponsor

Zealand University Hospital

Enrollment

408 participants

Start Date

May 8, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to evaluate the efficacy of screening for liver disease with liver stiffness measurement on abstinence or light consumption after 6 months in individuals who are receiving treatment for alcohol use disorder and without a history of liver disease. The investigators will conduct a randomized controlled trial with concealed allocation comparing A) an invitation to a liver stiffness measurement, blood sampling and leaflet on alcohol-related disease (intervention) with B) an invitation to blood sampling (control). The primary outcome is 'abstinence or light consumption' (≤ 10 units/week) throughout the last months, and assessed 6 months after randomization.


Eligibility

Min Age: 18 YearsMax Age: 110 Years

Inclusion Criteria2

  • Attending outpatient treatment for alcohol use disorder (international classification of disease version 10: F102: alcohol dependence or F101: harmful alcohol use) at Novavi Køge or Novavi Roskilde
  • Informed written consent

Exclusion Criteria2

  • Not speaking Danish or English
  • Severe liver disease (known by the participant)

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Interventions

DIAGNOSTIC_TESTTransient Elastography

One transient elastography 1-2 weeks after randomization


Locations(2)

Novavi Køge

Køge, Denmark

Novavi Roskilde

Roskilde, Denmark

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NCT05855031


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