Alcohol Use Disorder Clinical Trials

211 recruitingLast updated: June 18, 2026

There are 211 actively recruiting alcohol use disorder clinical trials across 22 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1, Phase 4. Top locations include New Haven, Connecticut, United States, Bethesda, Maryland, United States, Providence, Rhode Island, United States. Updated daily from ClinicalTrials.gov.


Alcohol Use Disorder Trials at a Glance

211 actively recruiting trials for alcohol use disorder are listed on ClinicalTrialsFinder across 6 cities in 22 countries. The largest study group is Not Applicable with 102 trials, with the heaviest enrollment activity in New Haven, Bethesda, and Providence. Lead sponsors running alcohol use disorder studies include Yale University, National Institute on Alcohol Abuse and Alcoholism (NIAAA), and Washington State University.

Browse alcohol use disorder trials by phase

Treatments under study

About Alcohol Use Disorder Clinical Trials

Looking for clinical trials for Alcohol Use Disorder? There are currently 174 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Alcohol Use Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Alcohol Use Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 211 trials

Recruiting
Phase 1

Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)

Alcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)176 enrolled1 locationNCT07559500
Recruiting
Phase 1Phase 2

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 1

Environment and Alcohol: A Pilot Study

Alcohol Use Disorder
National Institute on Drug Abuse (NIDA)44 enrolled1 locationNCT06860607
Recruiting
Phase 1

PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder

Alcohol Use Disorder
National Institute of Mental Health (NIMH)30 enrolled1 locationNCT06795581
Recruiting
Phase 1

Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)

Alcohol Use Disorder
National Institute of Mental Health (NIMH)30 enrolled1 locationNCT07027839
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting

Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)

Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)475 enrolled1 locationNCT05677321
Recruiting

Hepatic Lipid Metabolism-Alcohol Use Disorder

Alcohol Use Disorder
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)25 enrolled1 locationNCT07191561
Recruiting
Not Applicable

Drinking, Acetate, and Stress

Alcohol Use DisorderAlcohol Use, UnspecifiedHeavy Drinker+1 more
Yale University50 enrolled2 locationsNCT06584448
Recruiting
Phase 2Phase 3

Alcohol Use Disorder and Cannabidiol

Alcohol Use Disorder
University of Colorado, Denver180 enrolled1 locationNCT05613608
Recruiting

Imaging Phosphodiesterase 4B (PDE4B) in People With Psychiatric Disorders With Positron Emission Tomography (PET) and the Radiotracer [18F]PF974

Post Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Yale University160 enrolled1 locationNCT07488819
Recruiting
Early Phase 1

Suvorexant and Alcohol

Alcohol Use Disorder
William Stoops30 enrolled1 locationNCT06326684
Recruiting
Not Applicable

Better Experiences in Substance Treatment: A Brief Alcohol-focused Intervention Tailored for Patients in Opioid Agonist Treatment

Opioid UseOpioid-use DisorderAlcohol Use Disorder+1 more
University of Notre Dame60 enrolled1 locationNCT07342504
Recruiting
Not Applicable

Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH

Alcoholic HepatitisAlcohol Use Disorder
Johns Hopkins University200 enrolled1 locationNCT03845205
Recruiting
Phase 2

Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder

Alcohol Use Disorder
Yale University80 enrolled1 locationNCT07029529
Recruiting
Phase 1

Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers

Heavy DrinkerAlcohol ConsumptionAlcohol Use Disorder (AUD)
Yale University63 enrolled2 locationsNCT06136195
Recruiting
Not Applicable

Optimizing Smart Technology for Addiction Recovery

Alcohol Use DisorderAlcohol Use Disorder (AUD)
University of Wisconsin, Madison416 enrolled1 locationNCT07573540
Recruiting
Not Applicable

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)

AlcoholismAlcohol Use DisorderAlcohol Dependence+3 more
Brainsway186 enrolled9 locationsNCT07216872
Recruiting
Not Applicable

An Effectiveness Trial of the PrEP for WINGS Study

HIV InfectionsAlcohol Use DisorderViolence, Gender-Based
Columbia University307 enrolled1 locationNCT06853314
Recruiting
Not Applicable

Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection

Alcohol Use DisorderHuman Immunodeficiency Virus
Rush University Medical Center40 enrolled1 locationNCT06139224