RecruitingPhase 4NCT05856136
A Study to Investigate of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle
Investigation of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle to Generate Higher Force Behaviors
Sponsor
Mayo Clinic
Enrollment
69 participants
Start Date
Jun 19, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to evaluate opioid dose effects on the ability of the diaphragm muscle to generate higher force behaviors.
Eligibility
Min Age: 18 Years
Inclusion Criteria1
- \- Adult male and female patients undergoing lower extremity orthopedic surgery at the study institutions (St. Mary Hospital and Rochester Methodist Hospital within the Mayo Clinic Rochester hospital system).
Exclusion Criteria3
- Patients who refuse research participation.
- Patients who are pregnant.
- Patients with known pulmonary pathology (COPD, asthma requiring routine treatment).
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Interventions
DRUGFentanyl Injection
Three different fentanyl doses (used for sedation) will be evaluated on their effects on shear wave elastography (SWE) and breathing
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05856136
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