Intra-arterial Alteplase for Acute Ischemic Stroke After Mechanical Thrombectomy
Intra-arterial Alteplase for Acute Ischemic Stroke After Mechanical Thrombectomy (PEARL): A Multicenter, Prospective, Open-label, Blinded Endpoint, Randomized Controlled Trial
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
324 participants
Aug 1, 2023
INTERVENTIONAL
Conditions
Summary
A multicenter, prospective, open-label, blinded endpoint, randomized controlled trial aiming at evaluating the efficacy and safety of intra-arterial recombinant human tissue plasminogen activator (rt-PA) after successful recanalization of acute large vessel occlusion in the anterior circulation by mechanical thrombectomy in improving the 90-day functional outcome.
Eligibility
Plain Language Summary
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Interventions
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Locations(2)
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NCT05856851