RecruitingNCT05858307

Clinical Application of Serum Anti-Müllerian Hormone (AMH) Measurements


Sponsor

Chinese University of Hong Kong

Enrollment

300 participants

Start Date

Jun 22, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to assess the association of Anti-Müllerian hormone (AMH) with polycystic ovarian syndrome, premature ovarian insufficiency and fertility. The main objectives include the following: 1. To study the level of serum AMH in women with PCOS and to evaluate the utility of serum AMH in the diagnosis of PCOS. 2. To evaluate the level of serum AMH in women with POI and to evaluate the utility of serum AMH in the management of POI. 3. To evaluate the associations of basal AMH level with FSH level and AFC respectively for women undergoing ART treatment. 4. To determine the optimal regimen of gonadotropin for ovarian stimulation for women undergoing ART treatment. 5. To evaluate the predictive value of serum AMH in reproductive outcomes including oocyte quality, embryo quality, pregnancy loss, clinical pregnancy and live birth rate in women undergoing ART treatment.


Eligibility

Sex: FEMALEMin Age: 10 YearsMax Age: 44 Years

Plain Language Summary

Simplified for easier understanding

This study is examining how a hormone called Anti-Müllerian Hormone (AMH) — which reflects ovarian health and egg supply — changes over time and in response to fertility treatments. It focuses on women with polycystic ovary syndrome (PCOS) or premature ovarian insufficiency (POI), and those undergoing IVF (in vitro fertilization). **You may be eligible if...** - You are a woman between 10 and 44 years old - You are being treated for PCOS or POI at the relevant clinic, OR - You are undergoing IVF or assisted reproductive technology (ART) treatment **You may NOT be eligible if...** - You are younger than 10 or 45 years old or older - You have a medical condition that affects hormone levels or how hormones are processed by the body Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.


Locations(1)

The Chinese University of Hong Kong

Hong Kong, Hong Kong

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05858307


Related Trials