Acute Cardiac Dysfunction in Critical Illnes
Aetiology and Clinical Importance of Acute Cardiac Dysfunction in Critical Illness
Sahlgrenska University Hospital
592 participants
May 29, 2023
OBSERVATIONAL
Conditions
Summary
The overall aim of the study is to establish the clinical importance of cardiac dysfunction, by estimating its incidence and impact on short- and long-term outcomes, in a mixed population of critically ill patients with multi-organ failure. Pathogenesis of cardiac dysfunction in critical illness and key molecules linked to this will be explored.
Eligibility
Inclusion Criteria6
- Patients aged \> 18 years
- Admitted to a participating ICU within 24 hours
- Significant organ dysfunction involving at least two organ systems. This is defined as fulfilling both of the following:
- At least 4 points on the SOFA scale (Sequential Organ Failure Assessment scale)
- Having at least 1 point on the SOFA scale from at least two organ systems
- Given informed consent from patient or permission to participate from next of kin
Exclusion Criteria3
- Echocardiographic examination not possible (e.g., pneumothorax, draping etc) or very low echocardiographic examination quality
- Not being examined with echocardiography within 24 hours from inclusion
- Retracted consent to participate
Interventions
All patients in the study will be examined with echocardiography
Sub-group of patients with left ventricular systolic dysfunction will be examined with cMRI
Sub-group of patients with left ventricular systolic dysfunction will be examined with CCT
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05860504