RecruitingNCT05869760

Baylor Infant and Toddler Biomarker of Nutrition Study

Observational Validation of Skin Carotenoid Biomarker of Infant and Toddler Carotenoid Intake


Sponsor

Baylor College of Medicine

Enrollment

208 participants

Start Date

Jun 26, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Young children rely on their foods and drinks for the nutrients they need to grow, like energy, protein, vitamins, and minerals. In addition to nutrients, there are substances in fruits, vegetables, milk and formula, called phytochemicals, that can support health. While researchers know more about the role of phytochemicals in adult health, researchers know surprisingly little about how phytochemicals can support health in young children. One group of phytochemicals are called the carotenoids. Carotenoids are responsible for the red, orange, and yellow colors in some fruits and vegetables. In adults, carotenoids can support visual function. Researchers also know that measuring levels of carotenoids in the blood or optically in the skin, can serve as an indirect measurement of what child and adults eat. The purpose of this study is to determine how a child's usual intake of carotenoids is related to their visual development and their blood and skin levels of carotenoids. The study involves 6 visits. For each visit, we will ask about the child's recent diet, will measure their body size, collect a blood sample, collect optical measurements of their skin, and will test how sharp their vision is.


Eligibility

Min Age: 3 MonthsMax Age: 24 Months

Inclusion Criteria5

  • healthy
  • born at term (more than or equal to 37 weeks gestation)
  • between the 1st to 99th weight for age percentile at 3 months of age
  • participating guardian speaks, reads, and understands English
  • guardian categorizes child as non-Hispanic white, Hispanic white, Asian, or non-Hispanic Black

Exclusion Criteria3

  • physician-diagnosed metabolic, absorptive, or endocrine condition
  • diagnosed food intolerance or allergy
  • has a sibling enrolled in the study

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERCarotenoid Intake

Carotenoid intake calculated from food diary records reported by guardians.

OTHERSerum carotenoid concentrations

Serum carotenoid concentrations measured by HPLC.


Locations(1)

USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine

Houston, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05869760


Related Trials