CRATOS - Evaluation of Cratos™ Branch Stent Graft System in Treatment of Descending Aorta Lesions

This study evaluates the Cratos Branch Stent Graft System — a specialized endovascular device — for treating diseases of the descending thoracic aorta, including dissections and ulcers that require placement in a specific landing zone involving the left subclavian artery (the artery supplying the left arm). Thoracic aortic diseases can be life-threatening, and traditional open surgery carries high risk. The Cratos device is designed to allow minimally invasive repair while maintaining blood flow to critical branch vessels like the left subclavian artery. Adult patients aged 18 or older with thoracic aortic pathology deemed to need surgical repair, appropriate aortic anatomy confirmed by CT imaging, and adequate vessel dimensions in the treatment zone are eligible. Patients with recent stroke or heart attack, active infection, connective tissue disorders (like Marfan syndrome), severe kidney disease, or pregnancy are excluded. Participants will undergo the endovascular procedure with the Cratos device and be followed for clinical outcomes including procedural success, complications, and aortic health over time. This study matters because it could validate a less invasive option for treating complex thoracic aortic disease, improving survival and recovery compared to open surgery for patients who may not tolerate it well.