RecruitingEarly Phase 1NCT05874310

Gene Therapy for Subjects With RPGR Mutation-associated X-linked Retinitis Pigmentosa

An Open-label, Single-center, Dose-escalation Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Intraocular Administration of FT-002 in Subjects With RPGR Mutation-associated X-linked Retinitis Pigmentosa.


Sponsor

Frontera Therapeutics

Enrollment

18 participants

Start Date

Feb 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

A clinical trial of gene therapy for patients with X-linked retinitis pigmentosa (XLRP).


Eligibility

Sex: MALEMin Age: 8 YearsMax Age: 45 Years

Inclusion Criteria1

  • Subjects that are willing and able to follow study procedures; 2.Males aged 8-45 years old at the time of signing the Informed Consent Form; 4.Subjects who are confirmed with variants of RPGR ;

Exclusion Criteria1

  • Have other retinal degenerative diseases, such as retinal degeneration caused by other known Inherited retinal disease gene variants or previously received an gene therapy product.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

GENETICFT-002

Comparison of different dosages of FT-002


Locations(2)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

Eye & ENT hospital of Fudan university

Shanghai, Shanghai Municipality, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05874310