RecruitingNot ApplicableNCT05874479

Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents

Sponsor

NYU Langone Health

Enrollment

440 participants

Start Date

Dec 20, 2023

Study Type

INTERVENTIONAL

Conditions

Blood Pressure

Summary

Fine particulate matter \<2.5 µm (PM2.5) air pollution is the fifth leading risk factor for global mortality, with the largest portion of deaths due to cardiovascular disease (CVD). While several mechanisms are responsible, PM2.5-induced elevations in blood pressure (BP) may be relevant. Indoor portable air cleaners (PACs) are a novel approach to reduce exposure to PM2.5 and potentially lower blood pressure. The current study is being conducted to provide evidence that PACs reduce PM2.5 exposure and lower systolic blood pressure (SBP) in key patient populations.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria2

self-reported nonsmokers living in a nonsmoking household.
adults living with hypertension (HTN) from NYC public housing.

Exclusion Criteria13

History of major known arrhythmias (e.g. atrial flutter or fibrillation, ventricular tachycardia).
Screening systolic BP ≥160 mm Hg or diastolic BP ≥100 mm Hg (i.e. severe hypertension by the 2017 ACC/AHA BP guideline).
A change in drug regimen in the prior 2 weeks or a planned change in drug regimen during the first 30 days for those taking antihypertensive medication.
Current smoking or living with an active smoker who smokes indoors
Planned travel out of NYC for ≥2 weeks in next 6 months
Incarcerated
Pregnant
Unable/unwilling to consent
Established cardiovascular disease
End-stage renal disease (chronic kidney disease stage IV or on dialysis)
Barrier to technology use (e.g., visual or hearing impairment)
Lung disease requiring oxygen
Cancer receiving treatment