RecruitingNCT05875155

Ovarian Tissue Cryopreservation for Fertility Preservation

Ovarian Tissue Cryopreservation for Fertility Preservation in Patients Facing Infertility-causing Diseases or Treatment Regimens

Sponsor

University of Pittsburgh

Enrollment

500 participants

Start Date

Jan 13, 2011

Study Type

OBSERVATIONAL

Conditions

Cancer Autoimmune Diseases

Summary

The goal of this observational study is to learn about fertility preservation for pre-pubertal, peri-pubertal, and adult participants that are unable to pursue clinical standard of care fertility preservation such as egg (oocyte) and embryo cryopreservation. In addition, this study will provide research tissue for the following Specific Aims: 1. To optimize techniques for cryopreservation of ovarian tissues from patients at significant risk for infertility. 2. To investigate factors affecting successful maturation ovarian tissue. Participants will undergo a surgical procedure to remove an ovary (oophorectomy) to preserve their gonadal tissue for fertility preservation.

Eligibility

Sex: FEMALEMax Age: 39 Years

Plain Language Summary

Simplified for easier understanding

This study is for women who need to preserve their fertility before undergoing medical treatment — such as surgery, chemotherapy, or radiation — that may permanently damage their ovaries. The study collects ovarian tissue by surgery, freezes it, and may later reimplant it to restore fertility. **You may be eligible if...** - You are female and under 40 years old - You are about to undergo cancer treatment or another medical procedure that could permanently stop your ovaries from working - You are unable or unwilling to use egg or embryo freezing alone - You have a condition requiring removal of one or both ovaries - You have been newly diagnosed or have a recurrence without having previously received treatments that permanently stop ovarian function **You may NOT be eligible if...** - You have a psychological or psychiatric condition that prevents you from giving fully informed consent - You have a medical condition that significantly increases your risk from anesthesia or surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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