Adaptive Radiation for Abdominopelvic Metastases

This study tests adaptive radiation therapy — a highly precise form of radiation that adjusts to changes in the tumor's shape and location over time — for patients with cancer that has spread to the abdomen or pelvis. The goal is to precisely target tumors in these regions with fewer side effects. **You may be eligible if...** - You are over 18 with any type of solid cancer that has spread to the abdomen or pelvis - You have at least one untreated tumor in your abdomen or pelvis that can be measured on scans - Your health is good enough for radiation (ECOG 0–1) - Your estimated survival is at least 12 months - Your blood counts and organ function are within acceptable ranges **You may NOT be eligible if...** - You have peritoneal carcinomatosis (cancer spreading throughout the belly lining) - You have 6 or more active metastatic sites - You have cancer outside the abdomen/pelvis that is actively progressing - You have received prior radiation to any target tumor site - You are pregnant or breastfeeding - You have uncontrolled infection, heart failure, or psychiatric illness that affects compliance Talk to your doctor to see if this trial is right for you.