RecruitingNot ApplicableNCT05888571

Pre-pectoral Breast Reconstruction With or Without Mesh

A Randomized Controlled Trial of Prepectoral Breast Reconstruction With and Without Mesh


Sponsor

Tianjin Medical University Cancer Institute and Hospital

Enrollment

164 participants

Start Date

Jul 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

To explore the efficacy and safety that occur after immediate prepectoral breast reconstruction when TiLOOP Mesh is used compared to that when TiLOOP Mesh is not used.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 65 Years

Inclusion Criteria7

  • Adult women aged 18-65 years who plan to undergo unilateral or bilateral immediate prepectoral prothesis breast reconstruction;
  • SSM or NSM or Skin-Reducing Mastectomy for breast cancer patients or prophylactic mastectomy;
  • Tissue expander size =\<800cc, implant size =\<600cc;
  • The blood perfusion of breast skin flap was well;
  • Do not smoking in the last 4 weeks or more
  • Patients with normal expectations and mental health for breast reconstruction;
  • Signed consent to participate

Exclusion Criteria5

  • Poor perfusion of breast mastectomy flap;
  • II stage breast reconstruction patients;
  • History of chest radiotherapy;
  • BMI greater than 35;
  • Patients who have not quit smoking within the last 4 weeks;

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Interventions

PROCEDUREprepectoral breast reconstruction

Patients receive immediate prepectoral breast reconstruction

PROCEDURETiloop Mesh implantation

Patients receive immediate prepectoral breast reconstruction with Tiloop Mesh


Locations(1)

Tianjin Medical University Cancer Institute and Hospital

Tianjin, Tianjin Municipality, China

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NCT05888571


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