RecruitingNot ApplicableNCT05890287

A Study of Chidamide Plus Endocrine in Maintenance Treatment of HR+/HER2- Breast Cancer After First-line Chemotherapy

An Open, Single-center, Exploratory Cohort Study of Chidamide in Combination With Endocrine in Maintenance Therapy After First-line Chemotherapy for HR+/HER2- Breast Cancer


Sponsor

Tianjin Medical University Cancer Institute and Hospital

Enrollment

60 participants

Start Date

May 16, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

To explore the efficacy and safety of Chidamide combined with endocrine for maintenance therapy after first-line chemotherapy for HR+/HER2- breast cancer


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether adding chidamide (a drug that affects gene regulation) to hormone therapy can help maintain remission in women with hormone receptor-positive, HER2-negative breast cancer after completing first-line chemotherapy. **You may be eligible if...** - You are a woman aged 18–70 - You have HR+/HER2- breast cancer confirmed by biopsy - Your cancer is locally advanced or has spread to distant organs - You have completed first-line chemotherapy and achieved at least stable disease **You may NOT be eligible if...** - You have HER2-positive breast cancer - You have not responded to or completed first-line chemotherapy - You are outside the 18–70 age range Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGChidamide

Chidamide+ exemestane/Fulvestrant/Letrozole/Anastrozole/Tamoxifen


Locations(1)

天津市肿瘤医院

Tianjin, China

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NCT05890287


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