Trial of an Exercise Intervention for Children With Haemophilia
Development Of a haemophiLia PHysiotherapy INtervention for Optimum Musculoskeletal Health in Children (DOLPHIN-II) - a Randomised Controlled Trial
East Kent Hospitals University NHS Foundation Trust
132 participants
May 6, 2021
INTERVENTIONAL
Conditions
Summary
"Being able to participate in games and activities with their friends" is one of the things that matters most to boys with haemophilia. At present, there is a lack of robust evidence to determine whether muscle strengthening exercise can improve or negatively affect outcomes for young children with haemophilia. With the help of boys with haemophilia, their parents and physiotherapists the investigators have developed an exercise programme designed to increase muscle strength. Using this intervention the investigators will undertake a single-blinded, two-arm pragmatic randomised controlled trial (RCT) of a 12-week intervention verses usual care of boys with haemophilia aged 6-12 years of age.
Eligibility
Inclusion Criteria1
- • Children aged 6-12 years, with severe or moderate haemophilia A or B
Exclusion Criteria5
- von Willebrand disease
- past history of fracture or trauma to the lower limb
- orthopaedic surgery
- acquired brain injury or any other disturbance of the central nervous system; joint or muscle bleed in the lower limb in the past 6 weeks
- presence of lower limb pain or unable to fully comply with verbal instructions.
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Interventions
12-week exercise intervention
usual care
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05895032