RecruitingNCT05899439

Immune Function and the Progression to T1D

Immune Function and the Progression to Type 1 Diabetes:


Sponsor

University of Florida

Enrollment

2,800 participants

Start Date

Jan 1, 2005

Study Type

OBSERVATIONAL

Conditions

Summary

To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.


Eligibility

Min Age: 0 YearsMax Age: 100 Years

Exclusion Criteria1

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Interventions

OTHERblood draw

a peripheral blood draw


Locations(3)

Kieran McGrail

Gainesville, Florida, United States

The Ohio State University

Columbus, Ohio, United States

Baylor College of Medicine, Center for Research Advancement - Texas Children's Hospital

Houston, Texas, United States

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NCT05899439


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