Clinical One-stage Controlled Study of reSistant Arterial Hypertension for the desiGning of a personAlized Approach to Therapy

This study is looking at whether a personalized approach to treating resistant high blood pressure — where standard medications haven't worked well enough — leads to better blood pressure control. It involves testing different combinations of blood pressure medications. **You may be eligible if...** - You have been diagnosed with high blood pressure according to established guidelines - You have already made lifestyle changes as recommended - You have been taking two blood pressure medications (lisinopril, amlodipine, or valsartan) combined with indapamide for at least one month at stable doses - If you are a woman of childbearing age, you are using reliable contraception throughout the study **You may NOT be eligible if...** - You are involved in running or organizing this study - You are pregnant Talk to your doctor to see if this trial is right for you.