RecruitingNCT05908279

Gait Control in Parkinson Disease

Flexible Control of Gait in Parkinson Disease: Effect of Task Instruction on the Exploitation of Redundancy in Speed Control.


Sponsor

Université Catholique de Louvain

Enrollment

100 participants

Start Date

May 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Previous work has shown that a statistical property of gait characterised by long-range autocorrelation functions is altered in Parkinson disease (PD). On the other hand it has been suggested that the same property is linked to the ability in healthy humans to co-regulate the amplitude and cadence of strides towards maintaining a constant speed. Here the investigators want to better understand why it is altered in PD by measuring the transitions between gait instructed by a metronome, and gait without metronome. The experimental conditions will allow the comparisons between these transitions across PD and healthy groups of volunteers, and assess differences based on statistical and computational modelling. The link with potential freezing episodes will also be studied to assess whether the statistical determinants of gait control in this population can be used as a proxy or predictor of the occurence of freezing episodes.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Inclusion Criteria1

  • Patients and volunteers able to walk for 20mins and without other neurological disorders.

Exclusion Criteria1

  • Patients or volunteers unable to walk for 20mins and with other neurological disorders.

Interventions

OTHERWalking test

Walk with and without a metronome

OTHERDisease assessement

Disease stage assessed by a doctor


Locations(1)

Université catholique de Louvain

Louvain-la-Neuve, Belgium

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NCT05908279


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