LEft Bundle branchArea Pacing to Avoid Pacing-induced CARdiomyopathy
LEft Bundle branchArea Pacing to Avoid Pacing-induced CARdiomyopathy: the LEAP-CAR Prospective, Randomized Trial
Azienda Ospedaliero Universitaria Maggiore della Carita
130 participants
Jun 10, 2023
INTERVENTIONAL
Conditions
Summary
LEAP-CAR will evaluate the benefit of left bundle branch area pacing (LBBAP), comparing to conventional right ventricular pacing (RVP), in preventing pacing-induced cardiomyopathy (PICM) in patients undergoing pacemaker implant for advanced (2° or 3° degree) atrioventricular block, with baseline left ventricular ejection fraction (LVEF) \>45%. LEAP-CAR is a randomized, prospective, double blind clinical trial.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Pacing of the conduction system of the heart to obtain physiological activation
Conventional ventricular pacing
Locations(1)
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NCT05910866