RecruitingPhase 2NCT05913180

Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries

Vitamin C for the Prevention of Catheter-associated Urinary Tract Infections in Women Who Undergo Elective Gynecological Surgeries: a Randomized Double-blinded Controlled Trial


Sponsor

American University of Beirut Medical Center

Enrollment

180 participants

Start Date

Sep 19, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Double-blind placebo-controlled randomized trial aiming to assess the role of Vitamin C supplementation in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 80 Years

Inclusion Criteria3

  • Nonpregnant women
  • years of age or older
  • Undergoing elective GYN surgery

Exclusion Criteria13

  • Pregnant women
  • Already taking Vitamin C supplementation
  • Nephrolithiasis
  • Congenital anomaly or neurogenic bladder
  • Allergy to ascorbic acid
  • On therapeutic anticoagulant medicine during the 6 weeks after surgery
  • Gynecological surgery involving fistula repair or a vaginal mesh removal
  • Positive Urinalysis in the pre-admission unit
  • Recurrent UTIs
  • Diabetes
  • G6PD
  • Hemochromatosis
  • Renal disorders

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Interventions

DRUGAscorbic Acid 1000 MG

1000mg Ascorbic acid orally daily started on the day of elective gynecological surgery for 10 days

DRUGPlacebo

Placebo tablet daily starting day of elective gynecological surgery for 10 days


Locations(1)

Moscow State University of Medicine and Dentistry

Moscow, Russia

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NCT05913180


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