RecruitingNot ApplicableNCT05917717

Cardiac Arrest Bundle of cARE Trial

Cardiac Arrest Bundle of Care Trial


Sponsor

University Hospital Southampton NHS Foundation Trust

Enrollment

32 participants

Start Date

May 24, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

An out-of-hospital cardiac arrest is a sudden event where the heart stops beating and a person becomes unresponsive. During this event, vital organs in the body receive no blood flow, causing them to shut down. Without intervention to restart the heart, a person effectively dies. In the UK, around 60,000 people experience cardiac arrests each year, with most occurring at home. Despite prompt emergency service response, survival rates are typically low. There is technology available that has the potential to improve survival rates for out-of-hospital cardiac arrests. The intervention involves three devices used together: head-up position CPR (Elegard), active compression-decompression mechanical CPR (Lucas-3), and the Impedance Threshold device (Resqpod-16). When combined, these devices can enhance blood flow during resuscitation, potentially leading to improved initial resuscitation rates and higher rates of survival with normal brain function after a cardiac arrest. A pilot study is planned to test the feasibility of using these devices. The results will inform the design of a larger study to determine if this technology can indeed improve survival rates in out-of-hospital cardiac arrests.


Eligibility

Min Age: 18 YearsMax Age: 120 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Neuroprotective 'bundle of care' for people with cardiac arrest, cardiopulmonary resuscitation, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURENeuroprotective 'bundle of care'

This includes the 3 devices: * Head up cardiopulmonary resuscitation (HUP-CPR) * Active compression decompression CPR * Impedance threshold device (ITD)


Locations(1)

University Hospital Southampton NHS Foundation trust

Southampton, England, United Kingdom

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NCT05917717


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