Padeliporfin VTP Using Robotic Assisted Bronchoscopy in Peripheral Lung Cancer

This study is testing a light-activated treatment called padeliporfin VTP (vascular targeted photodynamic therapy) delivered through a robotic bronchoscope to destroy small peripheral lung tumors — those located near the outer edges of the lung. The treatment is done before standard surgery to see if it can effectively kill tumor cells while preserving healthy lung tissue. **You may be eligible if:** - You are 18 or older - You have a small lung lesion (tumor up to 2–3 cm) that is suspected or confirmed to be primary lung cancer - Your tumor is located in the outer part of the lung, at least 2 cm away from major airways and major blood vessels - Your tumor is not attached to or very close to the outer lung surface (pleura) - A multidisciplinary team has approved you for this bronchoscopic procedure before surgery - You can tolerate bronchoscopy under general anesthesia - Your organ function is adequate and life expectancy is at least 3 months **You may NOT be eligible if:** - Your tumor is centrally located near major airways or large blood vessels - Your tumor is larger than the allowed size limit - You have lymph node involvement detected at the time of bronchoscopy - You have certain conditions that make bronchoscopy or general anesthesia unsafe Talk to your doctor to see if this trial is right for you.