RecruitingNot ApplicableNCT05918835

Effects of rTMS on Food Choice in Anorexia Nervosa

Deciphering the Neural Mechanisms of Restrictive Eating in Anorexia Nervosa Using Repetitive Transcranial Magnetic Stimulation


Sponsor

New York State Psychiatric Institute

Enrollment

72 participants

Start Date

Apr 24, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This study will examine the impact of high-frequency repetitive transcranial magnetic stimulation on food choice behavior and related neural activity.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called High-frequency repetitive transcranial magnetic stimulation (active rTMS) and a medical device called Sham repetitive transcranial magnetic stimulation (sham rTMS) for people with anorexia nervosa. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years to 35 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEHigh-frequency repetitive transcranial magnetic stimulation (active rTMS)

HF-rTMS is applied with a figure-of-8 coil using the Magstim TMS System. Participants receive one administration of HF-rTMS, delivered to the region of the right dorsolateral prefrontal cortex (DLPFC) with greatest resting-state functional connectivity to the dorsal striatum (individualized per participant). HF-rTMS is delivered at a frequency of 10 Hz for approximately 37 minutes (3000 total pulses).

DEVICESham repetitive transcranial magnetic stimulation (sham rTMS)

Sham rTMS is applied with a figure-of-8 sham coil using the Magstim TMS System, which is identical to the active coil, replicates the sounds of HF-rTMS, and is designed to mimic sensations of HF-rTMS. Participants receive one administration of sham rTMS, delivered to the region of the right dorsolateral prefrontal cortex (DLPFC) with greatest resting-state functional connectivity to the dorsal striatum (individualized per participant). Sham rTMS is delivered for approximately 37 minutes (3000 total pulses).


Locations(1)

New York State Psychiatric Institute

New York, New York, United States

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NCT05918835


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