Nasal Obstruction and Olfactory Losses
Novel Mechanisms and Therapeutic Approaches for Nasal Obstruction and Olfactory Losses
Ohio State University
330 participants
Jan 25, 2023
INTERVENTIONAL
Conditions
Summary
About 13% of US adults, some 30 million people, suffer from nasal sinus disease. Although nasal obstruction and smell loss are two of the major symptoms of the disease that are crucial to disease management, currently there is a lack of clinical tools to effectively evaluate the mechanisms contributing to these symptoms. The proposed study aims to develop novel clinical tools to better evaluate and relieve patients' nasal obstructive symptoms and to enable patients and clinicians to make more informed, personalized decisions regarding treatment strategy.
Eligibility
Inclusion Criteria2
- Smell Loss complaints
- Nasal Obstruction
Exclusion Criteria6
- Congenital olfactory losses
- Nasal polyps, blocking the olfactory cleft
- Significant atrophy
- Cystic fibrosis
- Wegeners or any other connective tissue disorder
- Head trauma
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Interventions
Please see the arm description for details.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05920330