RecruitingNCT05920824

Atrial Functional Mitral Regurgitation and Tricuspid Regurgitation

Clinical Phenotypes, Risk Factors, & Determinants of Outcome in Functional Mitral and Tricuspid Valve Regurgitation


Sponsor

Barts & The London NHS Trust

Enrollment

141 participants

Start Date

Dec 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

A prospective, observational cohort study designed to identify clinical phenotypes and evaluate predictors \& outcomes of functional mitral and tricuspid valve regurgitation in patients with atrial fibrillation. Participant will under go: * Baseline echocardiography * Cpex Echocardiography * Blood test: BNP * 1 year follow up Echocardiography Participants will be stratified into three subgroups: * Atrial Functional MR * Atrial Functional TR * Mixed MR \& TR


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Informed consent
  • Age of 18 years or older
  • Atrial fibrillation
  • Moderate or severe atrial valve disease
  • Adequate 2D echocardiography views including parasternal long axis, short axis, apical two chamber, apical three chamber and four chamber.

Exclusion Criteria3

  • Unwilling or unable to give consent
  • Left ventricular impairment (ejection fraction \< 50%).
  • Primary/organic valve disease

Interventions

DIAGNOSTIC_TESTEchocardiogram

Ultrasound scan of the heart


Locations(1)

St Bartholomew's Hospital

London, United Kingdom

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NCT05920824


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