Do Patients Who Received Tranexamic Acid in Vaginal Hysterectomy Loose Les Blood, Comparing to Patients Who Did Not?
Do Patients Who Are Treated With Tranexamic Acid Loose Les Blood, Comparing to Patients Who Are Not Treated, During Vaginal Hysterectomy? a Randomized Control Study
Wolfson Medical Center
80 participants
Jan 22, 2023
INTERVENTIONAL
Conditions
Summary
This is a randomized control, double-blind study in which women who are about to go an elective vaginal hysterectomy are offered to participate. Patients will be randomly assigned to one of two groups: the tranexamic acid group, in which 1 gram of tranexamic acid (Hexakapron) is administered intravenously before surgery, and the control group, in which patients will receive 10 ml of normal saline 0.9% intravenously.
Eligibility
Inclusion Criteria1
- \*Women in general good health (defined as American Society of Anesthesiologists grade 1-2) who are about to undergo elective vaginal hysterectomy indicated by pelvic organ prolapse (POP).
Exclusion Criteria7
- allergy to TXA
- familial or personal history of hypercoagulability disorder or thromboembolic events
- impaired renal function or hematuria
- patients receiving antithrombotic therapy
- additional concurrent abdominal/ laparoscopic procedures
- malignancy
- Post-assignment exclusion will be executed in cases of conversion to laparotomy/ laparoscopy.
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Interventions
One gram of tranexamic acid (Hexakapron) is administered intravenously before surgery
patients will receive 10 ml of normal saline 0.9% intravenously.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05921071