a Cohort Study of Ischemic Cerebrovascular Disease
a Prospective, Multicenter Cohort Study of Ischemic Cerebrovascular Disease
Xiangya Hospital of Central South University
5,000 participants
Nov 1, 2022
OBSERVATIONAL
Conditions
Summary
This study aims to establish a multicenter, large-scale, prospective cohort of patients with ischemic stroke. Various biological samples such as blood, feces, and urine are collected to identify biomarkers associated with ischemic stroke. By integrating demographic information, clinical indicators, imaging parameters, and biomarker parameters, the study aims to develop risk assessment, early warning, and prognosis prediction models. Additionally, the study aims to identify key genes and explore relevant signaling pathways related to ischemic stroke.
Eligibility
Inclusion Criteria3
- Clinical diagnosis of ischemic stroke.
- Age ≥ 18 years.
- Signed informed consent form.
Exclusion Criteria6
- Patients with moderate to severe mental disorders or dementia who cannot cooperate to complete the informed consent and follow-up procedures.
- Patients with neurological functional impairment caused by conditions such as migraine aura, epilepsy, or other non-ischemic strokes.
- Agitated patients who cannot cooperate with imaging examinations.
- Pregnant or lactating patients, as well as those planning to become pregnant within 90 days.
- Patients with concurrent malignant tumors or severe systemic diseases with an expected survival period of less than 90 days.
- Patients who have participated in other clinical studies within 30 days prior to enrollment or are currently participating in other interventional clinical studies.
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Interventions
Intravenous thrombolysis with alteplase within the time window of stroke onset in stroke patients
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05922540