RecruitingPhase 4NCT05927233

Effect of Methylprednisolone on Systemic Inflammatory Response During Pediatric Congenital Open-Heart Surgery

Effect of Methylprednisolone on Systemic Inflammatory Response and Clinical Parameters During Pediatric Congenital Open-Heart Surgery: A Randomized Controlled Trial

Sponsor

Aga Khan University

Enrollment

60 participants

Start Date

Apr 1, 2023

Study Type

INTERVENTIONAL

Conditions

Cyanotic Heart Disease Cardiopulmonary Bypass

Summary

The goal of this study is to evaluate the effects of steroids on the early postoperative inflammatory response in patients undergoing elective pediatric congenital cardiac surgery, requiring cardiopulmonary bypass (CPB).

Eligibility

Min Age: 1 MonthMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Methylprednisolone and a drug called Saline for people with cardiopulmonary bypass and cyanotic heart disease. The study is currently recruiting participants at 1 location. People eligible for this study include aged 1 Month to 18 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMethylprednisolone

30 ml Methylprednisolone (30mg/kg) with a maximum dose of 500 mg

DRUGSaline

30 ml Normal saline

Locations(1)

Aga Khan University Hospital

Karachi, Sindh, Pakistan

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NCT05927233

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