A Randomized Clinical Trial Comparing Chi-BEAM With BEAM Regimen Combined With ASCT for the Treatment of ND PTCL

This study compares two conditioning regimens (Chi-BEAM vs standard BEAM) used to prepare patients with peripheral T-cell lymphoma (a type of aggressive blood cancer) for an autologous stem cell transplant — where your own stem cells are used to rebuild your immune system after high-dose chemotherapy. **You may be eligible if...** - You have been newly diagnosed with peripheral T-cell lymphoma (excluding certain types) - Your cancer has responded to first-line treatment (complete or partial remission) - You are between 18 and 65 years old - Your heart, lung, kidney, and liver function meet the required levels - You have enough stem cells collected for transplantation - Your general health score (ECOG) is 0 or 1 **You may NOT be eligible if...** - Your lymphoma has spread to the brain or spinal cord - You have active hepatitis B, C, or HIV - You have active infection or cirrhosis - Your heart shows significant electrical abnormalities (QTc over 500ms) Talk to your doctor to see if this trial is right for you.